CorMedix to buy Heron Therapeutics' assets for $145M cash plus stock

  • CorMedix agreed to acquire substantially all Heron Therapeutics assets for $145M in cash plus 14,583,333 CorMedix shares, with up to $55M in earn-outs tied to 2028 ZYNRELEF sales.
  • The deal adds ZYNRELEF, APONVIE, CINVANTI and SUSTOL; CorMedix targets $45-60M in cost synergies and a $150M Pharmakon term loan.
  • Closing is expected in Q1 2027, pending Heron stockholder approval and HSR clearance.
💡 Points Based on public reports

This moves CorMedix from a one-product story built on DefenCath into a broader hospital-focused commercial platform, with four products sold to the same institutional buyers. The earn-out tied to 2028 ZYNRELEF sales suggests the buyer is hedging on that product's uptake against entrenched competitors such as Exparel. The $45-60M synergy target and new term loan make integration execution the next test.

CorMedix Therapeutics to Acquire Substantially All Assets of Heron Therapeutics, Expanding Its Portfolio of Products Used in Institutional Settings of Care ↗